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I really haven't be able to look into Drugs but I see it as having a lot of potential. The big thing is making them appealing enough that people in the end will be comfortable with taking them oftently and potentially getting addicted. You will have to forgive me if these suggestions and what not are already in game but here are some ideas as follows.

Stamina Regeneration Boost - All that adrenaline is good for something. Being on this is the same as running around while sleeping on a bed (maybe)

Stamina exhaustion reduction ( Less stamina used while fighting or wearing armor)

Increase Pool Amount - A drug that relaxes your mind so that you may learn more skills at one time , or allow you to pool in more skills without becoming bewildered.

Increase Pool Speed - Being drugged up allows you to pour XP into your skills a little quicker.

Charming - Being drugged up has given you quite the charm boosting your APP by 1. (Maybe a side effect is that it will drop down by 1 or two after)

Numb the Pain - Allows you to fight un-impaired or at least not as much while you are injured.

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These are just some ideas I thought of right away, I'm pretty sure everyone else can think of something that could contribute (some of what I suggested might already exist)

Just a edit: These drugs should all have addiction and negative side effects.

A couple of these items do exist in game already, as drugs (mv regen) or cosmetics (+1 App score). I haven't tested them extensively, myself - just wanted to let the OP know that some of their wishes are already granted. :)

I think if you don't have the skill, you can't see the descriptions of the various concoctions but I know there are plenty of herbalists in game that would probably love to sell you on something.

Yeah, drugs are already in, including stimulants, depressants, painkillers, poisons, other stuff. Also they already have additiction, and some have side effects.

There was a push to use them when they came out, but no one seemed to care. I'm sure if you're interested in trying some it would not be hard to find a source for pretty much anything.

Heaven wrote:I

Numb the Pain - Allows you to fight un-impaired or at least not as much while you are injured.

So LCD or Bath Salts.. That could be interesting. I however do like the ideas of the drugs that affect your pooling. However there would need to be a downside to it.